Dr. Ketan Prasad Kulkarni, MD

Appointments:

Professor, Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia (January 2014 – Present)

Professor, Faculty of Medicine, Dalhousie University, Departments of Hematology, Pharmacy and Pathology (September 1, 2015 onwards)

Affiliations:

IWK Health Centre & Dalhousie University

Research Interests:

Supportive care in pediatric oncology, pediatric thrombosis, clinical outcome research, multiomics, genomics, microbiome

I have been interested in studying adverse events related to cancer and its therapy, complications associated with central venous catheters, and survival outcomes. To advance research and knowledge in the same, I am actively engaged in collaboration with basic and translational researchers in pharmacy, pharmacology, gastroenterology, immunology, cancer biology, mathematics and bioinformatics, and epidemiology amongst others to find innovative ways of improving the care of pediatric hematology oncology patients. I attempt to focus on using advanced technologies to improve care and outcome of children with cancer. I am also interested in studying thrombosis in high risk pediatric populations such as oncology, cardiology, intensive care and neonatology.

Involvement with BHCRI to date:

Dr. Ketan Kulkarni is an Associate Member

Phone:

(902) 470-3795

Email:

ketan.kulkarni@iwk.nshealth.ca

Contact:

Department of Pediatrics, Division of Hematology/Oncology, IWK Health Centre, 5850/5980 University Avenue, PO Box 9700, Halifax, NS B3K 6R8

Publications:

Forbrigger, Kuhle S, Brown MM, Moorehead PC, Digout C, Kulkarni K. The association of venous thromboembolism with survival in pediatric cancer patients: A population-based cohort study. Ann Hematol. 2018;97:1903-1908. https://doi.org/10.1007/s00277-018-3371-0 (Note: Trainee as lead author) Role: Lead and senior investigator

P.-Marcotte M-C; Pole J; Kulkarni K, Athale U, Stammers D, Brandão LR, Sung L. Thrombo-embolism in children with cancer: a population-based study. Thromb Haemost.  2018;118:1646-1655. doi: 10.1055/s-0038-1668543. Role: Co-investigator

Maclean J, MacDonald T, Digout C, Smith N, Rigby K, Kulkarni K. Need for tissue plasminogen activator for central venous catheter dysfunction is significantly associated with thrombosis in pediatric cancer patients. Pediatr Blood Cancer. 2018;65:e27015. doi:10.1002/pbc.27015. (Note: Trainee as lead author) Role: Lead and senior investigator

Truong T, Pole J, Barber R, Dix D, Kulkarni K, Martineau E, Randall A, Stammers D, Strahlendorf C, Strother D, Sung L. Enrollment on clinical trials does not improve survival for children with acute myeloid leukemia: a population-based study. Cancer. 2018124:4098-4106. doi: 10.1002/cncr.31728 Role: Co-investigator

Kulkarni K, Muia J, Boulaftali Y, Blondon M, Lauw M. Early career professionals: a challenging road. Res Pract Thromb Hemost.2018;2:11-13. https://doi.org/10.1002/ rth2.12070 Role: Lead author

Strahlendorf C, Pole J, Barber R, Dix D, Kulkarni K, Martineau E, Randall A, Stammers D, Strothers D, Truong T, Onysko J, Sung L. Does enrolling children with ALL on a clinical trial make a difference? A population based study. Br J Cancer. 2018; 118,744 749. Doi:10.1038/bjc.2017.462 Role: Co-investigator

Borretta L, MacDonald N, Digout C, Smith N, Fernandez C, Kulkarni K. Management Experience of Peripherally inserted central catheters in Pediatric Oncology Patients: A 15 year Population-Based review from Maritimes, Canada. J Pediatr Hematol Oncol.2018;40:e55–e60 (Note: Trainee as lead author) Role: Lead and senior investigator

Asyyed Z, MacDonald T, Digout C, Kulkarni K. Incidence and characteristics of venous thrombotic events in pediatric cancer patients: A 20-year experience in the Maritimes, Canada. Pediatric Hematol Oncol.2017;34:90-99 (Note: Trainee as lead author) Role: Lead and senior investigator

Pole J, Barber R, Bergeron R, Caret AS, Dix D, Kulkarni K, Martineau E, Randall A, Stammers D, Strahlendorf C, Strothers D, Truong T, Sung L. Most children with cancer are not enrolled on a clinical trial in Canada: a population-based study. BMC Cancer.17DOI:10.1186/s12885-017-3390-3396 Role: Co-investigator

Kulkarni KP. The continuing evolution of technology in cancer care. Future Oncol.2016;12:1961-1965 Role: Lead author