Appointments:
Research Director, Division of Plastic Surgery; Program Director, Clinician-Investigator Program and Medical Research Graduate Program; Associate Professor, Departments of Surgery and Microbiology & Immunology, Dalhousie University
Head, Division of Plastic & Reconstructive Surgery, IWK Health Centre
Affiliations:
Dalhousie University; IWK Health Centre
Research Interests:
breast cancer; melanoma; adipose-derived stem cells; fibrosis; cancer-associated fibroblasts; post-oncologic reconstruction.
For many patients, cancer treatment doesn’t end with the removal of a tumor, but when the whole patient has been restored through reconstruction. My research examines ways of optimizing reconstructive techniques such as autologous fat grafting and minimizing post-operative scarring and fibrosis while reducing the risk of cancer recurrence.
What brought you to your current institution? Dalhousie University and the IWK Health Centre allow me to seamlessly balance my research and clinical commitments as a surgeon-scientist.
Hometown: Toronto
Involvement with BHCRI to date:
I am a Senior Scientist and I have served on the steering committee for past Terry Fox Research Institute student symposia and have supervised CRTP trainees.
Email:
Contact:
IWK Health Centre, 5850/5980 University Avenue, PO Box 9700, Halifax, Nova Scotia, Canada, B3K 6R8
Publications:
Murphy AM, Wong AL, Bezuhly M. Modulation of angiotensin II signaling in the prevention of fibrosis. Fibrogenesis Tissue Repair. 2015 Apr 23;8:7.
Phipps KD, Gebremeskel S, Gillis J, Hong P, Johnston B, Bezuhly M.
Alternatively activated M2 macrophages improve autologous Fat Graft survival in a mouse model through induction of angiogenesis. Plast Reconstr Surg. 2015 Jan;135(1):140-9.
Gupta R, Brace M, Taylor SM, Bezuhly M, Hong P. In search of the optimal processing technique for fat grafting. J Craniofac Surg. 2015 Jan;26(1):94-9.
Gillis JA, Gebremeskel S, Phipps K, Johnston P, Hong P, Bezuhly M.
N-Acetylcysteine (NAC) Improves Free Autologous Fat Graft Survival: A Preclinical Study. Plast Reconstr Surg. 2014 Oct;134(4 Suppl 1):70-1
Gebremeskel S, LeVatte T, Liwski RS, Johnston B, Bezuhly M. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136(1):234-40.
Bezuhly M, Bucholtz J, Sigurdson L. Less scarring or more symmetry?
Reconstruction following metachronous bilateral breast cancer. J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1595-7.
Bezuhly M, Temple C, Sigurdson LJ, Davis RB, Flowerdew G, Cook EF Jr. Immediate postmastectomy reconstruction is associated with improved breast cancer-specific survival: evidence and new challenges from the Surveillance, Epidemiology, and End Results database. Cancer. 2009 Oct 15;115(20):4648-54.
Bezuhly M, Cullen R, Esmon CT, Morris SF, West KA, Johnston B, Liwski RS. Role of activated protein C and its receptor in inhibition of tumor metastasis. Blood. 2009 Apr 2;113(14):3371-4.