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  • Dr. Zhenyu Cheng, PhD


Assistant Professor, Department of Microbiology and Immunology


Dalhousie University

Research Interests:

Antibiotic Persistence, Bacteriology, Cancer Biology, Host Defence, Microbial Pathogenesis, Genomics and Proteomics

The overall research plan in the Cheng lab is to identify signaling components in both host immunity and bacterial pathogenesis pathways and to establish a framework for placing these diverse components into an integrated network, and then to use the knowledge from these studies to develop novel strategies to defend against pathogen attack. In addition, we also study the signal transduction events involved in various diseases, including cancers and developmental diseases. 

Involvement with BHCRI to date:

Dr. Zhenyu Cheng is an Associate Member


(902) 494-7829




Sir Charles Tupper Medical Building, Dalhousie University, 5850 College Street, P.O. Box 15000, Halifax, Nova Scotia, Canada B3H 4R2


Cheng Z.*, Li J.-F.*, Niu Y., Zhang X.-C., Woody O.Z., Xiong Y., Djonovic S., Millet Y., Bush J., McConkey B.J., Sheen J., and Ausubel F.M. *contributed equally. (2015) Pathogen-secreted proteases activate a novel plant immune pathway. Nature 521:213-216 

Zhang X.-C., Millet Y., Cheng Z., Bush J., and Ausubel F.M. (2015) SGT1b/HSP70/HSP90 chaperone complexes play an essential role in jasmonate signaling in Arabidopsis. Nature Plants 1(5):Article number 15049 

Cheng Z., Woody O.Z., Song J., Glick B.R., and McConkey B.J. (2009) Proteome reference map for the plant growth-promoting bacterium Pseudomonas putida UW4. Proteomics 9: 4271-4274 

Cheng Z., Wei Y.C., Sung W.W.L., Glick B.R., and McConkey B.J. (2009) Proteomic analysis of the response of the plant growth-promoting bacterium Pseudomonas putida UW4 to nickel stress. Proteome Science 7:18 

Cheng Z., Duan J., Hao Y., McConkey B.J., and Glick B.R. (2009) Identification of bacterial proteins mediating the interactions between Pseudomonas putida UW4 and Brassica napus (canola). Molecular Plant-Microbe Interactions 22:686-694

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