Dr. Scott A. Grandy
Associate Professor, School of Health & Human Performance and Department of Pharmacology, Dalhousie University
Affiliate Scientist, Division of Cardiology, Dept. of Medicine, NSHA Central Zone; Research Scientist, Atlantic Partnership for Tomorrow’s Health Study
Cardio-oncology, physical activity, cardiotoxicity
Dr. Grandy’s research focuses on the relationship between cardiovascular disease (CVD) and cancer. Specifically, he is interested in how cancer treatments lead to increased risk of CVD in cancer survivors and why CVD increases the risk of certain types of cancer. He is also interested in how physical activity can be used to decrease the risk of cancer as well as reduce the cardiotoxic side effects of cancer treatments. His translational research uses a combination of preclinical, clinical and population health studies to better understand the relationship between CVD and cancer and how physical activity can be used to prevent treatment related CVD in cancer survivors.
Involvement with BHCRI to date:Dr. Scott Grandy is a BHCRI Associate Member
Contact:Dalplex (office, rm 214), Department of Pharmacology (Lab, rm 6K), Dalhousie University, PO Box 15000, Halifax, NS, B3H 4R2
- Lamoreaux E, Grandy SA & Langille M. (2017). Moderate exercise has limited but distinguishable effects on the mouse microbiome. mSystems. In press.
- Sweeney E, Cui Y, DeClercq V, Devichand P, Forbes C, Grandy SA, Hicks J, Keats M, Parker L, Thompson D, Volodarsky M, Yu ZM, Dummer TJB. (2016). Cohort profile: The Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) study. International Journal of Epidemiology. In press.
- Martelli L, Saraswat D, Dechman G, Giacomantonio NB & Grandy SA. (2017). The Community Balance and Mobility Scale (CBMS) is a valid tool to assess balance in cardiac rehabilitation patients. Journal of Cardiopulmonary Rehabilitation and Prevention. In Press.
- Keats MR, Cui Y, Grandy SA and Parker L. (2017). Physical activity, cardiovascular disease risk factors and major cardiovascular events in adult cancer survivors: A nested, retrospective study from the Atlantic PATH cohort. Journal of Cancer Survivorship, 11(2): 264-273.
- Keats MR, Grandy SA, Giacomantonio NB, MacDonald D, Younis T. (2016). EXercise to prevent AnthrCycline-based Cardio-Toxicity (EXACT) in individuals with breast or hematological cancers: a feasibility study protocol. Pilot and Feasibility Studies, 2: 44-54.
- Grandy SA, Rivard K, Paradis P, Nemer M, Allen BG, & Fiset C. (2011). Ventricular Ca2+ handling is altered in transgenic mice with cardiac specific over-expression of the human type I angiotensin II receptor. American Journal of Physiol. Heart Circulation Physiol., 39(5): H2018-27.