Dr. Pollen K. Yeung, BSc Pharm, PhD
Professor, College of Pharmacy and Department of Medicine
Pharmacokinetics, Metabolism, Biomarkers, Cardiovascular Protection, Anti-cancer drugs
Although many anti-cancer drugs are highly effective against susceptible cancers in chemotherapy, they are often associated with serious cardiac adverse effects; and resistance to drug therapy may develop after prolonged treatment. It has been postulated that cardiac adverse effects may be reduced by combining them with drugs or natural health products for treatment of cardiovascular disease. Our research interest is to investigate whether or not combining these anti-cancer drugs with cardiovascular protective agents would improve pharmacokinetics and minimize their cardiovascular toxicities. This will lead to development of novel drug combinations of anti-cancer drugs for cancer chemotherapy, resulting in improved patient outcomes, longer survival and better quality of life.