Dr. Michael Bezuhly, MD, MSc, SM, FRCSC, FAAP
Assistant Professor, Department of Surgery (Division of Plastic & Reconstructive Surgery); cross-appointed to Department of Microbiology & Immunology
IWK Health Centre; Dalhousie University Faculty of Medicine
Drug repurposing; interplay between wound healing, thrombosis, and tumour progression; adipose-derived stem cells and breast cancer; modulation of fibroblasts in desmoplastic reactions
Reconstruction following mastectomy is part of complete breast cancer care. Increasingly, a technique called autologous fat grafting is being used to restore soft tissue lost to cancer extirpation. Our group is exploring how adipose-derived stem cells in fat grafts may be used to impede tumour growth and improve reconstructive outcomes. Additionally, we are examining how agents used to reduce skin fibrosis may also be capable of modulating the desmoplastic reaction associated with malignant melanoma, thereby reducing the risk of metastasis.