Dr. Marya Ahmed, MSc, PhD
Assistant Professor, Department of Chemistry & Faculty of Sustainable Design and Engineering
University of Prince Edward Island
Biomaterials, Drug delivery, immunotherapy, drug resistant carcinoma, polymer peptide hybrids
The use of combination drugs to overcome aggressive, metastatic and resistant cancerous anomalies is a focus of leading cancer research today. The cocktail of chemotherapeutics generally involve simultaneous intake of multiple anticancer drugs by the patient with little or no-control on their stoichiometric and targeted delivery to the affected area. The research theme in Ahmed group focuses on the development of peptide-based nanocarriers for precise and targeted delivery of multiple drugs in cancer cells.
Involvement with BHCRI to date:Dr. Marya Ahmed is an Associate Member
Contact:K. C. Irving Chemistry Building, 550 University Ave., University of Prince Edward Island, Charlottetown, PEI, C1A 4P3
Ahmed, M. Peptides, Polypeptides and Peptide-Polymer Hybrids for Gene Delivery. Biomater. Sci., 2017, 5, 2188-2211.
Ahmed, M.; Kelley, S. O. Enhancing the Potency of Nalidixic Acid Towards a Bacterial DNA Gyrase with Conjugated Peptides. ACS Chem. Biol. 2017, 12, 2563-2569.
Jean, S. R.; Ahmed, M.; Lei, E. K.; Wisnovsky, S. P. Kelley, S. O. Peptide-Mediated Delivery of Chemical Probes and Therapeutics to Mitochondria. Acc.Chem. Res. 2016, 49, 1893-1902.
Narain, R.; Wang, Y.; Ahmed, M.; Lai, B.; Kizhakkedathu, J. Blood Components Interactions to Ionic and Non-ionic Glyconanogels. Biomacromolecules 2015, 16, 2990-2997.
Ahmed, M.; Pan, D.; Davis, M.E. Lack of in vivo Antibody Dependent Cellular Cytotoxicity with Antibody Containing Gold Nanoparticles. Bioconjugate Chem. 2015, 26, 812-816.
Ahmed, M.; Narain, R. Carbohydrate Based Materials for Targeted Delivery of Drugs and Genes to the Liver. Invited Review, Nanomedicine, 2015, 10, 2263-2288.
Ahmed, M.; Ishihara, K.; Narain, R. Calcium Mediated Formation of Phosphorylcholine based Polyplexes for Efficient Knockdown of Epidermal Growth Factor Receptors (EGFR) in HeLa Cells. Chem. Comm. 2014, 50, 2943-2946.
Ahmed, M.; Narain, R. Cell Line Dependent Uptake and Transfection Efficiencies of PEI-Anionic Glycopolymer Systems. Biomaterials 2013, 34, 4368-4376.
Ahmed, M.; Wattanaarsakit, P.; Narain, R. Recent Advances in the Preparation of Glycopolymer Bioconjugates. Eur. Polym. J. 2013, 49, 3010-3033.
Kotsuchibashi, Y.; Zhang, Y.; Ahmed, M.; Ebara, M.; Aoyagi, T.; Narain, R. Fabrication of FITC-doped Silica Nanoparticles and their Cellular Uptake. J. Biomed. Mat. Res. Part A, 2013, 101, 2090-2096.