Dr. Mark Joseph Filiaggi, PhD
Professor & Chair, Department of Applied Oral Sciences, Faculty of Dentistry
Cross-Appointments: School of Biomedical Engineering, Department of Radiology
Affiliated Scientist, Department of Diagnostic Imaging, QEII Health Sciences Centre
Biomaterials, biomedical devices, drug delivery
Novel and Potentially Multifunctional Chemotherapeutic Delivery Vehicles
Our research program is focused on the development of novel biomaterials and biomedical devices, with an emphasis on polyphosphate processing approaches that facilitate localized delivery of therapeutic agents, including anticancer drugs. Targeted applications include hepatocellular carcinoma (liver cancer), a challenging and often palliative condition for which chemotherapeutic agent delivery directly to the location of the tumor (and minimizing its impact on noncancerous cells) is being considered in conjunction with blocking of the tumor’s blood supply.