Dr. Karen Bedard, PhD
Associate Professor, Department of Pathology, Dalhousie University
Cross Appointment, Department of Pediatrics, Isaak Walton Killam Children’s Hospital
Affiliated Scientist, Division of Hematopathology, Nova Scotia Health Authority
Reactive Oxygen Species
Working as part of a collaborative team including clinicians, geneticists, and bioinformaticians, we are identifying mutations responsible for rare genetic disorders, including rare cancers. We use a combination of techniques including genotyping, genetic mapping, sequencing and Q-RT-PCR to identify the underlying genetic mutations. Our lab uses human cell culture models to study the impact of identified genetic variations on the function of particular genes, with a particular interest in the role of reactive oxygen species.