Dr. J. Patrick Murphy, MSc, PhD
Assistant Professor in the Department of Biology at University of Prince Edward Island
Adjunct Professor (FGS) in the Department of Pathology at Dalhousie
Cancer metabolism, proteomics, metabolomics, immune cell metabolism, small molecule function
Understanding Small Molecule Metabolite Function and Regulation
Our laboratory is interested in combining mass spectrometry-based approaches in proteomics and metabolomics to understand the cell biology of cancer and immune cells.
Small molecules form the basis of many of the chemical reactions necessary for life and perform many of their biological functions by interacting with proteins. The small molecules that proteins interact with in nature are either produced within the cell (endogenous) or by other cells or organisms (exogenous).
For many cancer cell-endogenous and exogenous small molecules we don’t know: 1) their function, and 2) how their production is regulated. Understanding these areas will help us to uncover new metabolically regulated pathways important in cancer and immunology and how they are interconnected. Our laboratory develops and applies new quantitative techniques in proteomics, metabolomics, and molecular biology to answer these questions.
Hometown: Kensington, PEI
What brought you to your current institution?
I came to UPEI because of the close-knit community of researchers and students. I also grew up here.
Learn More about my research: projects.upei.ca/murphylab