The Beatrice Hunter Cancer Research Institute logo
  • Dr. Francesca Di Cara, PhD

Appointments:

Assistant Professor 
Department of Microbiology and Immunology
Department of Pediatrics
Dalhousie University

Research Interests:

Peroxisomes, Innate immunity, Immunometabolism, Lipid signaling, Stem cells proliferation, Intestinal epithelium integrity and Homeostasis, host-pathogens/commensals interaction

Cancer cells often alter metabolism to support their malignant phenotype. My group studies peroxisomes, ubiquitous membrane-bounded organelles that play a central role in regulating various metabolic activities, such as the turnover of complex lipids and reactive oxygen species, as immunometabolic organelle. Emerging evidence shows peroxisomes function as pivotal signalling platforms that modulate a growing number of conserved oncogenic or tumour suppressor pathways. My group rely on the genetic of Drosophila melanogaster to determine the cellular networks that regulate peroxisome activity in cancer cells and identify the peroxisomal contributions to cancer-specific metabolic alterations important to drive malignancy. 

Involvement with BHCRI to date:

Dr. Di Cara is an Associate Member

Phone:

902-470-8131

Contact:

Room K8522, 8th Floor Immunol Research IWK Health Centre 5850/5980 University Avenue Halifax, NS B3K 6R8
Site by: Spectacle Group