Dr. Jason N. Berman, MD, FRCPC, FAAP
Professor, Department of Pediatrics, Division of Hematology/Oncology; cross appointed to Department of Microbiology & Immunology and Pathology; Staff Pediatric Hematologist/Oncologist, IWK Health Centre
Dalhousie University Faculty of Medicine, IWK Health Centre
Developing and using zebrafish models of Childhood cancers and Leukemia in particular to study the disease and test potential new therapies; cancer genetics; hematopoiesis and specifically mast cell development
Fishing for answers to leukemia
Dr. Jason Berman’s diverse and highly collaborative research program has applied zebrafish to investigate transcriptional regulation of mast cells; develop personalized therapy for childhood leukemia; determine key transcription factors and microenvironmental cytokines in cancer metastasis; and model bone marrow failure syndromes and hereditary retinal disorders. Dr. Berman and his team are the first to identify a mast cell equivalent in the zebrafish. They are currently using zebrafish to model allergic, inflammatory and malignant mast cell diseases.