Allyson Cook, BSc
Supervisor:Dr. Graham Dellaire
Program of Study:MSc candidate
Project Title:Characterization of the tumor suppressor functions of PRP4K
Research Background:The pre-mRNA processing factor 4 kinase (PRP4K) is an enzyme that is a novel biological marker in cancer but its function in tumour development and progression is unclear. The Dellaire laboratory discovered that breast and ovarian cancers that have low levels of this enzyme are more resistant to therapy and have worse prognosis. My research aims to determine the proteins that interact with this enzyme and how loss of PRP4K alters growth signalling in breast cancer and contributes to cancer spread by a process known as metastasis. Ultimately, the results of these studies will provide new knowledge about growth control in breast cancer and may provide new therapeutic targets for preventing metastasis.
Scholarships and/or Awards:
- Cancer Research Training Program (CRTP) Traineeship Award 2019
- Graduating Student Leader Award for UNB Saint John
Following the completion of my master’s degree, I aspire to pursue a career either in the field of medicine, or as a biomedical researcher.