Ryan Holloway, BSc, MSc
Supervisor:Dr. David Waisman
Program of Study:PhD
Project Title:Regulation of the cell surface protease receptor S100A10 in cancer cells through retinoic acid signalling
Scholarships and/or Awards:
- Cancer Research Training Program (CRTP) Traineeship Award 2016
- Graduate Student Collaboration Research Grant 2014
- Cancer Research Training Program (CRTP) Travel Award 2011
- NSERC undergraduate student research award (USRA) 2008
During his graduate studies, Ryan extensively investigated the involvement of the tumour microenvironment on cancer progression and the mechanisms of cancer cell metastasis. Characterizing these mechanisms can assist in development of novel treatments in fighting cancer; however, cancer cells can acquire resistance to these treatments over time. Hence, Ryan would like to continue investigating the mechanisms of chemoresistance in cancer cells and how we can stop these effects from happening in cancer treatments. Ryan plans to apply his scientific background in a career in industry/pharmaceuticals and also hopes to eventually develop programs to fund/train researchers and students.
Bharadwaj A, Bydoun M, Holloway R, and Waisman D. (2013). Annexin A2 Heterotetramer: Structure and Function. Int. J. Mol. Sci. 14:1-49.
Holloway RW, Bogachev O, Bharadwaj AG, McCluskey GD, Majdalawieh AF, Zhang L & Ro HS. (2012) J Biol Chem. 287(46): 39171-81