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  • Dr. Daniel Gaston, PhD

Appointments:

Clinical Laboratory Bioinformatician, Molecular Diagnostics, Division of Hematopathology, Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority

Assistant Professor, Department of Pathology, Dalhousie University

Affiliations:

Department of Pathology and Laboratory Medicine, Nova Scotia Health Authority; Department of Pathology, Dalhousie University

Research Interests:

Bioinformatics, Genomics, Cancer Genomics, Molecular Evolution

Membership Status:

Dr. Daniel Gaston is an Associate Member

Phone:

(902) 473-7219

Email:

daniel.gaston@dal.ca

Website:

medicine.dal.ca/departments/department-sites/pathology/our-people/our-faculty/daniel-gaston.html

Address:

Mackenzie Building, Room 511, Department of Pathology and Laboratory Medicine, QEII Health Sciences Centre, Halifax, NS

Publications:

Carter MD, Gaston D, Huang WY, Greer WL, Pasternak S, L TY, Walsh NM. (2018). Genetic profiles of different subsets of Merkel cell carcinoma show links between combined and pure MCPyV-negative tumors. Human Pathology. 71: 117-125 

Sinha N, Gaston D, Manders D, Goudie M, Matsuoka M, Xie T, Huang WY. (2018). Characterization of genome-wide copy number aberrations in colonic mixed adenoneuroendocrine carcinoma and neuroendocrine carcinoma reveals recurrent amplification of PTGER4 and MYC genes. Human Pathology. 73: 16-25. 

Salsman J, Stathakis A, Parker E, Chung D, Anthes LE, Koskowich KL, Lahsaee S, Gaston D, Kukurba KR, Smith KS, Chute IC, Léger D, Frost LD, Montgomery SB, Lewis SM, Eskiw C, Dellaire G.(2017). PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4. Scientific Reports. 7(45038): 45038 

Aung T, Ozaki M, Lee MC, Schlötzer-Schrehardt U, et al. (2017). Worldwide genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new common-variant susceptibility loci. Nature Genetics. 49(7): 993-1004. 

LeBlanc JJ, Pettipas J, Gaston D, Taylor R, Hatchette TF, Booth TF, Mandes R, McDermid A, Grudeski E. (2016). Outbreak of Norovirus GII.P17-GII.17 in the Canadian Province of Nova Scotia. Can J Infect Dis Med Microbiol. Vol 2016 

Fernandez-Murray JP, Prykhozhij SV, Dufay JN, Steele S, Gaston D, Nasrallah G, Coombs A, Liwski R, Fernandez C, Berman J, McMaster C (2016) Glycine and Folate Ameliorate Congenital Sideroblastic Anemia. PLoS Genetics: In Press Prykhozhij SV, Rajan V, Gaston D, Berman JN. (2015) CRISPR MultiTargeter: A Web Tool to Find Common and Unique CRISPR Single Guide RNA Targets in a Set of Similar Sequences. PLoS ONE 10(3): e0119372 

Gaston D, Hansford S, Oliveira C, Nightingale M, Pinheiro H, Macgillivray C, Kaurah P, Rideout A, Steele P, Soares G, Huang WY, Whitehouse S, Blowers S, LeBlanc MA, Jiang H, Greer W, Samuels M, Orr A, Fernandez CV, Ludman M, Penney L, Mcmaster CR, Huntsman D, Bedard K. (2014) Germline mutations in MAP3K6 are associated with familial gastric cancer. PLoS Genetics 10(10): e1004669 

Venkatesh J, Yu JW, Gaston D, and Park SW. (2015) Molecular evolution and functional divergence of X-intrinsic protein genes in plants. Molecular Genetics and Genomics 290(2):443-60 

Robitaille, JM; Gillett, RM; Leblanc, M; Gaston, D; Nightingale, M; Mackley, MP; Parkash, S; Hathaway, J; Thomas, A; Ells, A; Traboulsi, E; Héon, E; Roy, M; Shalev, S; Fernandez, C; MacGillivray, C; Wallace, K; McMaster, CR; Bedard, K (2014) Phenotypic Overlap Between Familial Exudative Vitreoretinopathy (FEVR) and Microcephaly Lymphedema Chorioretinal Dysplasia (MLCRD) Caused by KIF11 Mutations. JAMA Ophth 132(12):1393-9 

Tsaousis AD, Gentekaki E, Eme L, Gaston D, Roger AJ (2014) Evolution of the Cytosolic Iron-Sulfur Cluster Assembly Machinery in Blastocystis Species and Other Microbial Eukaryotes. Eukaryotic Cell. 13(1): 143-153 

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