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  • Dr. Roy Duncan, PhD

Appointments:

Professor, Department of Microbiology & Immunology; cross-appointed to Department of Pediatrics; cross-appointed to Department of Biochemistry and Molecular Biology.

Affiliations:

Dalhousie University Faculty of Medicine, IWK Health Centre, Canadian Centre for Vaccinology, Dalhousie Infectious Disease Research Alliance (DIDRA)

Research Interests:

membrane proteins; membrane fusion; virology; fusogenic liposomes to deliver liposome-encapsulated cancer therapeutics and vaccines inside cells; role of myopodin in cancer cell invasion

Engineering FAST proteins into weapons against cancer

Since discovering the fusion-associated small transmembrane (FAST) proteins in the 1990s, Dr. Roy Duncan has gone on to develop these proteins into powerful new strategies against cancer. He and his research team are using FAST proteins to create a fusogenic liposome system that selectively targets cancer cells and carries chemotherapy agents through the cell membrane to destroy the cancer cell. The researchers are also investigating myopodin, a newly discovered biomarker for invasive prostate and bladder cancer, to determine its role in the mechanisms of cancer-cell invasion and metastasis.

Membership Status:

Dr. Duncan is a BHCRI Senior Scientist, presented at the 2010 BHCRI Symposium and has been a supervisor for CRTP trainees.

Phone:

(902) 494-6770

Email:

roy.duncan@dal.ca

Address:

Sir Charles Tupper Medical Building, Dalhousie University Faculty of Medicine, 5850 College Street, P.O. Box 15000, Halifax, Nova Scotia, Canada B3H 4R2
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