Dr. Kirill Rosen, PhD
Professor of Pediatrics & Biochemistry and Molecular Biology, Dalhousie University
Senior Investigator, Atlantic Research Centre
Dalhousie University Faculty of Medicine, IWK Health Centre
understanding the mechanisms that allow epithelial cells to survive after detaching from their original location – a situation that allows them to develop into cancerous masses
Exploring cancer-causing cell-survival mechanisms
Most common cancers arise from the layer of cells that lines our organs. The layer is known as the epithelium; individual cells are called epithelial cells. When normal epithelial cells let go of the lining they die and are eliminated by our bodies. However, genetic mutations allow those epithelial cells that have become cancerous to survive after detaching from their original location. This acquired ability to survive is an essential part of the process that allows these cells to form tumours. By learning how this happens, we hope to find ways of stopping the cancer process in its tracks.