Dr. Catherine K. L. Too, PhD
Professor, Department of Biochemistry & Molecular Biology, cross-appointed to the Department of Obstetrics & Gynecology
Dalhousie University Faculty of Medicine
Prolactin receptor signal transduction, androgen receptor, breast cancer, prostate cancer
Prolactin action in cancers
Prolactin is produced by some cancer cells and acts as a local growth factor to stimulate cell proliferation. Dr. Catherine Too and her team have cloned several new genes whose levels are altered by prolactin. Their current research investigates the roles of prolactin-regulated carboxypeptidase-D, alpha 4-phosphoprotein (a component of the mTOR pathway) and their newly identified interacting protein partners in the growth and survival of prolactin-responsive breast and prostate cancers.