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  • Dr. Brent Johnston, PhD

Appointments:

Professor, Department of Microbiology & Immunology, joint-appointed to Department of Pediatrics, cross-appointed to Department of Pathology
Canada Research Chair in Inflammation and Immunity

Affiliations:

Dalhousie University Faculty of Medicine

Research Interests:

Mechanisms of immune activation and cell recruitment; adhesion molecules, chemokines, and cytokines; roles of NKT cells and γΔ T cells in inflammation and cancer

Stimulating natural immunity against cancer

Natural Killer T (NKT) cells are a rare population of white blood cells with the potential to become powerful natural allies in the body’s efforts to fight cancer. Dr. Johnston is studying how signalling proteins and receptors can be manipulated to stimulate the NKT cells to mount an aggressive immune response, and to direct that response to the primary tumour location to eliminate the cancer at its source. He and his team are also examining the effects of immune-modulating compounds on NKT cell anti-tumour activity.

Membership Status:

Dr. Johnston is a BHCRI Senior Scientist, has been a BHCRI Seminar Series presenter, a former member of the BHCRI Training Committee and a supervisor for CRTP trainees.

Phone:

(902) 494-5131

Email:

brent.johnston@dal.ca

Address:

Sir Charles Tupper Medical Building, Dalhousie University Faculty of Medicine, 5850 College Street, P.O. Box 15000, Halifax, Nova Scotia, Canada B3H 4R2
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