Craig Ayre, B.Ed, MSc
Supervisor:Dr. Sherri L. Christian
Program of Study:PhD in Biochemistry
Project Title:The Characterization of Extracellular Vesicles Released from B cells Following CD24 Stimulation.
Scholarships and/or Awards:
- Cancer Research Training Program (CRTP) Traineeship Award 2015
- Oral Presentation Award, Biannual BHCRI Conference, Nov 2014
- Fellow of the School of Graduate Studies (Memorial University of Newfoundland, 2013-2014)
- Barrowman Travel Award, Department of Biochemistry, Memorial University of Newfoundland
- First place Oral Presentation, Biochemistry Summer Symposium (2012 and 2013)
Craig is interested in understanding how cells respond to and interact with their environment and with each other. One method used by both health and cancerous cells is through the release of extracellular vesicles. These vesicles can carry proteins or genetic material between cells and may be used to influence cell survival, growth and the development or metastasis of cancer. Following his PhD, he intends to pursue opportunities in translational research to study extracellular vesicles, and how they can be used to detect or treat diseases like cancer.
Location:Memorial University of Newfoundland
Pallegar, NK., Ayre, DC., Christian, SL. (2014). Inhibition of Raf/MEK or PI3K/Akt is not sufficient to reverse the downregulation of CD24 expression mediated by oncogenic Ras. In Submission to BMC Cancer. MS ID:1547174822141688
Ayre, DC., Elstner, M., Moores, ES., Christian, SL. (2015). Dynamic Regulation of CD24 Expression and Release of CD24-Containing Microvesicles in Immature B cells in Response to CD24 Engagement. In submission to Immunology. MS ID: IMM-2015-3612