Dr. Conrad Fernandez, Hon BSc (Genetics), MD, FRCPC
Professor, Department of Pediatrics; Head Division of Pediatric Hematology/Oncology; Cross-appointed Departments of Bioethics, Graduate Studies, Medicine; Chair, Return of Results Committee, Children’s Oncology Group; Vice Chair Bioethics Committee, Children’s Oncology Group; Renal Tumors Steering Committee, Children’s Oncology Group.
IWK Health Centre, Dalhousie University
Wilms tumor, orphan disease, ethics
My research interests are in two main spheres of inquiry. The first is in Wilms tumor, the most common renal cancer in childhood. I am the chair of an international COG clinical trial examining children with low and standard risk Wilms tumor. The collaborations afforded through the renal tumors committee have allowed a number of clinical and basic science research projects in Wilms tumor. I am also active in empiric research in the field of ethics, in particular the return of genetic results to research participants. I am the co-lead in a Genome Canada project (IGNITE) in which this issue is one of the key objectives.
Membership Status:Dr. Fernandez is a BHCRI Senior Scientist and has presented at a CRTP ILS.
Address:IWK Health Centre PO Box 9700 5850 University Avenue Halifax, NS, B3K 6R8 Canada
Fernandez CV, Li N, Mullen E, Grundy P, Perlman E, Shamberger R, Ehrlich P, Dome J. Barriers to the enrolment of children in the Children’s Oncology Group
study of very low risk Wilms’ tumor. A report from the Children’s Oncology Group. J Pediatr Hematology Oncology. 2011. Oct;33(7):521-523. PMID
Tsangaris E, Klaassen R, Fernandez CV, Yanofsky R, Scherek E, Champagne J, Silva M, Lipton JH, Brossard J, Samson Y, Abish S, Steele M, Ali K, Dower N,
Athale U, Jardine L, Hand JP, Stephen D, Odame I, Canning P, Allen C, Beyene J, Dror Y. Genetic analysis of inherited bone marrow failure syndromes from
the CIMFR comprehensive cohort of Canadian patients. J Med Genet. 2011 Sep;48(9):618-28. Epub 2011 Jun 9.
McMurter B, Parker L, Fraser RB, Magee JF, Kozancyzn C, Fernandez CV. Parental Views on Tissue Banking in pediatric Oncology patients. Pediatr Blood
Cancer. 2011 (Dec)15;57(7):1217-21 (epub Jan 2010). PMID 21254370.
Marjerrison S, Fernandez CV, Price VE, Njume E, Hesseling P. The use of ultrasound in endemic Burkitt’s lymphoma in Cameroon. Pediatr Blood Cancer.
Shaw R, Issekutz AC, Fraser R, Schmit P, Morash B, Monaco-Shawver L, Orange JS, Fernandez CV. Bilateral adrenal EBV-associated smooth muscle tumors in a
child with a natural killer cell deficiency. Blood. 2012 (Apr);119(17):4009-401. (doi:10.1182/blood-2011-10-385377). PMID 22427204.
Brett Gardiner B, Morash B, Riddell C, Wang H, Fernandez CV, Yhap M, Berman JN. The Incidence and Prognostic Significance of 9p21 Abnormalities In
Pediatric Acute Lymphoblastic Leukemia Patients. Pediatric Blood Cancer 2012 (Jun);58(6):852-9. [Epub ahead of print Jul 27. doi: 10.1002/pbc.23285].
Alos N, Grant RM, Ramsay T, Halton J, Cummings EA, Miettunen PM, Abish S, Atkinson S, Barr R, Cabral DA, Cairney E, Couch R, Dix DB, Fernandez CV, Hay J,
Israels S, Laverdière C, Lentle B, Lewis V, Matzinger M, Rodd C, Shenouda N, Stein R, Stephure D, Taback S, Wilson B, Williams K, Rauch F, Siminoski K,
Ward L; STOPP consortium. High Incidence of Vertebral Fractures in Children with Acute Lymphoblastic Leukemia 12 Months After the Initiation of Therapy.
J Clin Oncology 2012 (Aug); 30(22):2760-7. (Epub 2012 Jun 25). PMID 22734031.
Fernandez CV, Ruccione K, Wells R, Long JB, Pelletier W, Hooke MC, Pentz RD, Noll RB, Baker J, O’Leary M, Reaman G, Adamson PC, Joffe S. Recommendations
for the return of research results to study participants and guardians: A report from the Children’s Oncology Group. J Clinical Oncology 2012;30:4573-
4579. (E pub 2012 Oct 29). PMID 23109703
Dome JS, Fernandez CV, Mullen EA, Kalapurakal JA, Geller JI, Huff V, Gratias EJ, Dix DB, Ehrlich PF, Khanna G, Anderson JR, Naranjo A, and Perlman EJ.
Children’s Oncology Group’s 2013 Blueprint for Research. Pediatric Blood Cancer 2013 Jun;60(6):994-1000. (E pub 2012 Dec 19). PMID:23255438.
Unguru Y, Joffe S, Fernandez CV, Yu A. Ethical issues for control arm patients after revelation of benefits of experimental therapy for neuroblastoma. J
Clinical Oncology. 2013 Feb 10;31(5): 641-63 (E pub 2013 January 7). PMID 23295797.