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  • Dharini Bharadwaj, PhD

Program of Study:

Postdoctoral Fellow, Biochemistry and Molecular Biology

Project Title:

Physiological function of plasminogen receptor S100A10(p11) in breast cancer tumorigenesis and metastasis

Scholarships and/or Awards:

  • Cancer Research Training Program (CRTP) Traineeship Award 2015
  • Cancer Research Training Program (CRTP) Travel Award 2012
  • Cancer Research Training Program (CRTP) Traineeship Award 2010
  • 2008, Norman and Bernice Harris Graduate Student Cancer Research Award University of Nebraska Foundation, University of Nebraska-Lincoln, Nebraska, USA
  • 2007 – 2008, Milton E. Mohr Fellowship University of Nebraska-Lincoln, Nebraska, USA
  • 2005, Travel Grant 2005 Nebraska Symposium on Interdisciplinary Graduate Science Research University of Nebraska-Lincoln, Nebraska, USA
  • 2005 – 2006, Nebraska Center for Cellular Signaling Fellowship Center of Biomedical Research Excellent (CoBRE), Omaha, Nebraska, USA
  • 2005, Best Poster Award Sigma Xi (Graduate Student Research Fair Poster Competition) University of Nebraska-Lincoln, Nebraska, USA
  • 2001, Merit Award for Outstanding Contributions Wheat Research and Development, Unilever Research Laboratories, Bangalore, India
  • 1999 – 2001, Process and Equipment Technology Innovation Awards (3 Annual Awards)Wheat Research and Development, Unilever Research Laboratories, Bangalore, India
  • 1994, Scholarship award for Highest Score in Organic Chemistry Mithibai College, University of Mumbai (Bombay), India.

Career Aspirations:

Dharini’s long term career goals are to further hone her skills in cancer biology, conduct independent research, contribute to the field of cancer research, and most importantly to be able to impart the knowledge gained by training and educating students.

Location:

Dalhousie University

Publications:

Bharadwaj AG, Bydoun M, Holloway, RW, Waisman, DM. Annexin A2 Heterotetramer: Structure and Function. Review. International Journal of Molecular Sciences, February 2013, Accepted

Holloway RW, Bogachev O, Bharadwaj AG, McCluskey GD, Majdalawieh AF, Zhang L, Pan X and Ro H-S. Stromal AEBP1 promotes mammary gland tumourigenesis via proinflammatory and hedgehog signaling. J. Biol. Chem. 2012, 287(46):39171-81

Bharadwaj AG, Goodrich NP, McAtee CO, Haferbier K, Oakley GG, Wahl JK 3rd, Simpson MA. Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling. Exp Cell Res. 2011, 317(8):1214-25

Zhang L, Bharadwaj AG, Casper A, Barkley J, Barycki JJ and Simpson MA. Hyaluronidase activity of human Hyal1 requires active site acidic and tyrosine residues. J Biol Chem. 2009, 284(14), 9433-42

Bharadwaj AG, Kovar JL, Loughman E, Elowsky C, and Simpson MA. Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing. Am J Pathol. 2009 174(3), 1027-36.

Bharadwaj AG, Rector K, and Simpson MA.: Inducible Hyaluronan Production Reveals Differential Effects on Prostate Tumor Cell Growth and Tumor Angiogenesis, J. Biol. Chem. 2007, 282(28), 20561-72.

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